Doxorubicin相关论文
Quercetin-borate acid ester crosslinked micelles combined with doxorubicin to overcome cardiotoxicit
The clinical application of doxorubicin(DOX), an effective anti-cancer drug, has been limited by side effects, especiall......
The synthesis of water-soluble quantum dots (QDs) has recently received extensive attention due to noninvasive detection......
Targeted inhibition of myeloid-derived suppressor cells in the tumor microenvironment by low-dose do
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Induction of apoptosis in osteogenic sarcoma cells by combination of tumor necrosis factor-related a
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声动力治疗(sonodynamic therapy，SDT)与光线治疗相比具有更深的组织穿透深度，因此受到了广泛的关注。然而，开发在肿瘤低氧环境中也具......
目的探讨聚乙二醇化脂质体多柔比星（PLD）致晚期乳腺癌患者速发型超敏反应与血浆抗聚乙二醇（PEG）抗体的相关性。方法研究设计为前瞻性非......
目的 建立动物模型,为探讨多柔比星外渗性损伤发生机制及采取相应的防护措施提供可靠的实验研究依据.方法 将20只昆明种小鼠随机分......
Polymeric nanoparticles of poly(2-oxazoline), tannic acid and doxorubicin for controlled release and
A straightforward coassembly strategy was developed for the preparation of polymeric nanoparticles driving by the interm......
目的探讨采用低频脉冲超声联合微泡治疗是否可以增加化疗药物——盐酸阿霉素在肿瘤组织中的转运效率。方法24只新西兰荷瘤兔被随机......
目的通过两种不同方式诱导乳腺癌耐药细胞株(MCF-7/ADM)，比较两种诱导方式的生物学特性。方法以乳腺癌MCF-7细胞株为亲本细胞，采用低......
1例32岁女性患者因滤泡性淋巴瘤给予注射用盐酸多柔比星脂质体注射液20 mg入5%葡萄糖注射液250 ml静脉滴注。静脉滴注开始约1 min......
GMI(Ganoderma Microsporum Immunomodulatory protein)是从小孢子灵芝中提取的一种免疫调节蛋白,它有着强的水溶性与低毒性。目前......
目的 通过吸附阿霉素的纳米铁碳复合磁性载体经猪肝动脉插管介入,观察靶区肝组织、非靶区肝组织及血清中阿霉素的药代动力学变化.......
目的 评价脂质体多柔比星+卡铂方案治疗复发性卵巢上皮性癌(卵巢癌)的疗效和副反应.方法 2003年7月-2007年12月间北京肿瘤医院妇瘤......
Novel multifunctional nanoparticles containing a magnetic Fe3O4@SiO2 sphere and a biocompatible block copolymer poly(eth......
Targeted combination therapy for glioblastoma by co-delivery of doxorubicin, YAP-siRNA and gold nano
The combination of brain targeting drug delivery systems and multi-modal intervention pose a promising therapeutic appro......
目的 合成靶向修饰型介孔硅纳米粒用作抗肿瘤药物传递载体,提高对肿瘤细胞的杀伤效力.方法 采用模板-水热法合成介孔硅,以氨基基团......
Peptide self-assembled nanomaterials have attracted more and more attention due to their wide applications such as drug ......
Protein nanoparticles containing Cu(Ⅱ) and DOX for efficient chemodynamic therapy via self-generatio
Chemodynamic therapy (CDT) refers to generating hydroxyl radical (·OH) in tumor sites via hydrogen peroxide (H202) cata......
Network pharmacological study on the mechanism of shenfu decoction in the treatment of cardiotoxicit
Objective: Doxorubicin is an efficient anthracycline drug for the treatment of tumor, however, its cardiotoxicity restri......
Reactive oxygen species and senescence modulatory effects of rice bran extract on 4T1 and NIH-3T3 ce
Objective:To determine the effect of rice bran extract (RBE) in combination with doxorubicin on 4T1 triple-negative brea......
Targeted inhibition of myeloid-derived suppressor cells in the tumor microenvironment by low-dose do
Background::High agglomeration of myeloid-derived suppressor cells (MDSCs) in neuroblastoma (NB) impeded therapeutic eff......
目的:合成配体多肽GE11修饰的DSPE-PEG2000,制备新型阿霉素靶向脂质体,并进行体外表征.方法:采用取代反应合成DSPE-PEG2000,加成反......
一、研究背景与目的 生物治疗(biotherapy)是继手术、化疗、放疗后肿瘤的第四大治疗模式。而生物化疗(biochemotherapy)又是生......
Wenyang Huazhuo Fang exerts transient receptor potential cation channel subfamily C member-dependent
OBJECTIVE: To determine the effect of Wenyang Huazhuo Fang (WHF),a Traditional Chinese Medicine decoction,on renal funct......
Transcatheter arterial chemoembolization has become an established drug delivery system for palliative or bridging treat......
Fabrication of doxorubicin and chlorotoxin-linked Eu-Gd2O3 nanorods with dual-model imaging and targ
It is urgent to find a technology accurately to better diagnose and treat to brain tumor. Eu-doped Gd2O3 nanorods (Eu-Gd......
目的运用代谢组学方法研究参麦方对于由阿霉素所造成的大鼠心肌损伤的保护作用,探讨参麦方在体内发挥药效的作用机制。方法通过超......
目的制备携载PSMA单克隆抗体的载阿霉素纳米泡,观察其基本特性和体内显影能力。方法机械震荡法制备靶向载药纳米泡,观察其形态、大......
目的探讨18F－2－(5－氟－戊基)－2－甲基丙二酸(18F－ML－10)PET/CT早期监测阿霉素(DOX)诱导的心脏毒性的可行性。方法将47只BALB/c小鼠按随机数字......
Induction of apoptosis in osteogenic sarcoma cells by combination of tumor necrosis factor-related a
Background Osteosarcoma is one of the most common primary malignant tumors of bone with poor prognosis.TNF-related apopt......
Background Cancer cells with overexpression of heat shock protein 27 (HSP27) are resistant to chemotherapeutic drug doxo......
Neoadjuvant Combination Chemotherapy with Pegylated Liposomal Doxorubicin and Vinorelbine for Locall
OBJECTIVE In China, vinorelbine plus an anthracycline is a common neoadjuvant regimen for locally-advanced breast cancer......
Efficiency against multidrug resistance by co-delivery of doxorubicin and curcumin with a legumain-s
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
目的制备新型载阿霉素纳米粒子,观察其理化性能,研究其对乳腺癌MDA-MB231细胞凋亡及在裸鼠体内的抑瘤作用,为三阴性乳腺癌的治疗提......
目的研究紫杉醇联合阿霉素治疗局部晚期乳腺癌的临床效果。方法选取广西梧州市工人医院2008—2015年收治的局部晚期乳腺癌患者110......
目的 观察阿霉素致心肌损伤大鼠的血清肌钙蛋白I(cTnI)、脑钠肽(BNP)、心肌细胞凋亡指数(AI)的变化及不同剂量红景天对该变化的影......
目的探讨雷帕霉素对耐药胃癌细胞对多柔比星敏感性的影响。方法用含低浓度(0.5μmol/L)多柔比星培养基培养并建立耐药胃癌细胞株MK......
目的探讨黄芪多糖对大鼠阿霉素性心衰的保护作用。方法取雄性SD大鼠30只,随机分为对照组、心衰模型组和黄芪多糖组,每组10只。黄芪......
Objective: To observe the influence of pH value on the proliferation of LAK cells and on the killing effect of rIL-2,IFN......
Background:Osteosarcoma is the most common bone malignancy in children and adolescents,and 20%-30%of the patients suffer......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
目的 探讨红细胞生成素(EPO)对阿霉素(DOX)性心肌病的预防性保护作用及可能机制.方法 31只Wistar大鼠随机分为DOX组(12只)、DOX+EP......
目的 探讨吡柔比星在膀胱原位癌(CIS)定位诊断中的效果.方法 在经尿道膀胱肿瘤电切(TUR-BT)术前膀胱内灌注吡柔比星(THP),术中在普......
目的 探讨蛋白激酶抑制剂N苯甲酰星孢菌素PKC412联合阿霉察对膀胱肿瘤细胞生长抑制及凋亡诱导作用及其机制,为膀胱癌治疗提供新理......
目的 研究多柔比星对乳腺癌MCF-7细胞增殖的影响,并探讨腺苷酸活化蛋白激酶(AMPK)在其中的作用.方法 分别用AMPK激活剂AICAR、siRN......
